Two elderly people in a Queensland aged care home have been given four times the correct amount of the coronavirus vaccine.
The 88-year-old man and 94-year-old woman are being monitored but are showing no signs of an adverse reaction.
They are both residents at the Holy Spirit Nursing Home in Carseldine.
The doctor responsible for the overdoses has resigned.
Health Minister Greg Hunt said the deputy chief medical officer would review the events and file a report.
"Significantly the patients themselves are showing, at this point, on the latest advice that I have, five minutes before joining us, absolutely no adverse reaction," he told reporters in Canberra today.
"The rollout continues. There will be cases. There will be challenges. This has happened in other jurisdictions overseas."