Britain's vote to leave the European Union adds a heavy dose of uncertainty to a world economy that is still struggling to reach full speed years after the global financial crisis.
The most immediate pain will be felt in Britain. But economists say the ripples could be felt much farther afield.
Companies will wonder whether to invest or locate in Britain during the years-long negotiations to define new trade conditions with the EU, its biggest business partner.
Across Europe, trade and immigration may lose ground to nationalism and protectionism.
The EU itself, minus market-oriented Britain, may turn to more government intervention and regulation. Other countries may eventually seek to leave the bloc.
Here's a look at what the vote means for the world economy:
The most direct economic pain will be felt by the UK, while the direct consequences for the world economy are likely to be more moderate.
Moody's Analytics estimates that global economic output would be 0.25 percent smaller after five years than it otherwise would have been, while the EU would be a full percent smaller and the UK 4 percent.
Then there are indirect effects. Stock market plunges can make people feel poorer and less likely to spend. Uncertainty can make executives put off investments in new production.
The market plunges following the vote are one reason for the world's central banks to keep their rock-bottom interest rates in place.
"Brexit could be a game changer for central bank thinking," Megan Greene, chief economist at Manulife Asset Management, wrote in a research note.
The Federal Reserve is less likely to raise short-term interest rates this year - and might even have to cut them.
Greene predicted that the Bank of England could have to print money to finance government spending, tax cuts or both and that the Bank of Japan could follow.
The London Lily Pad
Many big companies use the UK as a base for their European operations.
London's strength as a banking center is in part based on easy access to financial markets in Europe.
Regulatory approval to do business in the British capital means an all-access pass to the other 27 EU countries, a process called passporting.
Global banks like JP Morgan Chase have already said that they would have to move jobs from London to the European mainland if Britain leaves the EU.
The pound and euro both dropped, which should make British and eurozone exports cheaper overseas.
American travelers heading to Britain and the rest of Europe are going to find cheaper meals, hotels, souvenirs and museum admissions because the U.S. dollar will go farther against a weaker pound and euro.
Airfare for peak summer months probably won't dip but any taxes and fees levied in Europe will be cheaper.
For instance, all coach passengers leaving the UK for the US pay 73 pounds for the Air Passenger Duty. That tax is now cheaper.
The impact on UK-EU trade would depend on how quick and amicable negotiations are on a new set of relations.
Britain could wind up like Switzerland, which simply adopts EU requirements without having any say in how they are decided.
Britain sends 44 percent of its exports to the EU, less than any other member country but still quite significant.
The price for continued market access, however, could be allowing free movement of workers.
A desire to control immigration was a major force behind the "leave" campaign, so it's unclear if such an agreement could ever be reached.
Stock markets plunged yesterday, with Germany's DAX falling almost 7 percent, the Dow 2.6 percent and Britain's FTSE 3.2 percent. The pound hit a 31-year low.
Outside of the UK, however, that turmoil may not last. Analysts at Oxford Economics think the global market reaction and fears of an EU breakup are exaggerated.
The British vote have a much broader impact if becomes a political turning point away from trade and economic integration.
In economic terms, free trade is considered a plus for growth. It should mean bigger markets, lower consumer prices and more competition.
Yet those advantages can quickly be forgotten if people feel that the benefits are not fairly distributed, or that their jobs are left unprotected and move to other, lower-cost countries.
Many think a British exit could embolden anti-EU, anti-immigration political movements such as the Front National in France.
Its leader, Marine Le Pen, is already considered likely to make the final round of presidential elections next year.
Geert Wilders, head of the anti-Islam, anti-EU Freedom Party in the Netherlands, called Friday for a referendum on the EU there, too.
And it goes beyond Europe.
Donald Trump, the likely Republican nominee for U.S. president, has described the free trade agreement among Canada, the US and Mexico as "a disaster."