World 100 metre champion Christian Coleman will not compete at the Tokyo Olympics next year.
The American has been banned for two years for breaching whereabouts rules, according to the Athletics Integrity Unit (AIU).
Coleman was provisionally suspended in June after missing three doping tests.
"We impose on the athlete a period of ineligibility of two years, which will end on May 13, 2022," the AIU said in a statement.
"The decision may be appealed to the Court of Arbitration for Sport."
The sprinter at the time blamed anti-doping officials and claims they didn't follow procedure when he missed them after going Christmas shopping in December last year.