The Warriors have included 18-year old Isaiah Papali'i for their NRL round 22 clash with the Knights in Newcastle on Saturday, after a suspected pectoral injury ruled out second rower Bodene Thompson.
Papali'i made his first-grade debut in the opening round of the season, also against the Knights as the Warriors picked up a 26-22 win at Mt Smart Stadium.
Thompson had so far played every one of the Warriors' matches this season, scoring six tries.
His injury means that the Warriors will go into the match without their two most experienced players, being Thompson (143 NRL matches) and Ryan Hoffman (301 matches).
Rookie halfback Mason Lino keeps his spot in the run-on side with Shaun Johnson still ruled out with a knee injury.
Their opponents the Knights ended an eight match losing streak with a 21-14 victory over the Dragons on Saturday.
The Warriors however, have won the last four clashes between the two sides.
Warriors: 1. Roger Tuivasa-Sheck (c), 2. David Fusitu'a, 3. Blake Ayshford, 4. Solomone Kata, 5. Ken Maumalo, 6. Kieran Foran, 7. Mason Lino, 8. Jacob Lillyman, 9. Issac Luke, 10. Ben Matulino, 11. Isaiah Papali'i, 12. Bunty Afoa, 13. Simon Mannering.
Interchange (from): 14. Ata Hingano, 15. Sam Lisone, 16. Ligi Sao, 17. James Bell, 18. Jazz Tevaga, 20. Chris Satae, 21. Nathaniel Roache, 22. Charnze Nicoll-Klokstad.